Amtrak's "Capitol Limited" operates daily between Washington, DC And Chicago. It passes through West Virginia's Eastern Panhandle with stops in Harpers Ferry and Martinsburg.
Amtrak's "Cardinal" operates three days a week between Washington, DC and Chicago. It passes throught the soutthern part of the state with stops at White Sulphur Springs, Alderson, Hinton, Prince, Thurmond, Montgomery, Charleston and Huntington.
Maryland Rail Commuter (MARC) train service operates Monday through Friday between Martinsburg, WV and Washington, DC. The West Virginia State Rail Authority maintains staions at Harpers Ferry and Duffields.